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Summary: The Risk of Inflammatory
Bowel Disease Increased with Oral Contraceptive Use
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A
meta-analysis was made on 14 studies
done with 78,815 women between 1983
and 2007 and compared those using
the oral contraceptive pills and
those who never used them on the
etiology of Ulcerative Colitis and
Crohn’s Disease. Adjustments were
made for smoking. The
results showed that there is
evidence of an association between
the use of oral contraceptive agents
and the development of inflammatory
bowel disease, particularly Crohn’s
Disease. The overall average of
increased risk for inflammatory
bowel disease was 1.5 times. It
also suggests that the risk for
those who stop using OCPs reverts to
that of women who were not exposed
to them.1
1Cornish,
Et al., The Risk of Oral
Contraceptives in the Etiology of
Inflammatory Bowel Disease: A
Meta-Analysis, Am J
Gastroenterology 103:2394-2400,
2008
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